Late Outcomes of the RAPID-TnT Randomized Controlled Trial: 0/1-Hour High-Sensitivity Troponin T Protocol in Suspected ACS

High-sensitivity troponin assays are increasingly being adopted to expedite evaluation of patients with suspected acute coronary syndromes. Few direct comparisons have examined whether the enhanced performance of these assays at low concentrations leads to changes in care that improves longer-term o...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2021-07, Vol.144 (2), p.113-125
Hauptverfasser: Lambrakis, Kristina, Papendick, Cynthia, French, John K., Quinn, Stephen, Blyth, Andrew, Seshadri, Anil, Edmonds, Michael J.R., Chuang, Anthony, Khan, Ehsan, Nelson, Adam J., Wright, Deborah, Horsfall, Matthew, Morton, Erin, Karnon, Jonathan, Briffa, Tom, Cullen, Louise A., Chew, Derek P.
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Sprache:eng
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Zusammenfassung:High-sensitivity troponin assays are increasingly being adopted to expedite evaluation of patients with suspected acute coronary syndromes. Few direct comparisons have examined whether the enhanced performance of these assays at low concentrations leads to changes in care that improves longer-term outcomes. This study evaluated late outcomes of participants managed under an unmasked 0/1-hour high-sensitivity cardiac troponin T (hs-cTnT) protocol compared with a 0/3-hour masked hs-cTnT protocol. We conducted a multicenter prospective patient-level randomized comparison of care informed by unmasked 0/1-hour hs-cTnT protocol (reported to
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.121.055009