Endometrial endometrioid carcinoma, grade 1, is more aggressive in the elderly than in the young

Aims The aim of this study was to characterise grade 1 (G1) endometrioid carcinoma in the elderly, by using clinicopathological features and immunohistochemical features of surrogate markers of molecular subtypes. Methods and results We retrospectively analysed tumour samples from 268 patients with...

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Veröffentlicht in:	Histopathology 2021-11, Vol.79 (5), p.708-719
Hauptverfasser:	Hachisuga, Kazuhisa, Ohishi, Yoshihiro, Tomonobe, Hiroshi, Yahata, Hideaki, Kato, Kiyoko, Oda, Yoshinao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Cancer Carcinoma, Endometrioid - metabolism Carcinoma, Endometrioid - pathology elderly Endometrial Hyperplasia - metabolism Endometrial Hyperplasia - pathology Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Endometrium Female G1 endometrioid carcinoma Gynecology Humans Hyperplasia Medical prognosis Middle Aged Multivariate analysis Myometrium Neoplasm Grading Obstetrics p53 expression Prognosis Retrospective Studies shorter progression‐free survival Survival Tumor Suppressor Protein p53 - metabolism Tumors
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Zusammenfassung:	Aims The aim of this study was to characterise grade 1 (G1) endometrioid carcinoma in the elderly, by using clinicopathological features and immunohistochemical features of surrogate markers of molecular subtypes. Methods and results We retrospectively analysed tumour samples from 268 patients with G1 endometrioid carcinoma (
ISSN:	0309-0167 1365-2559
DOI:	10.1111/his.14400