Neonatal and maternal outcomes among twin pregnancies stratified by mode of conception in the United States

To compare neonatal and maternal outcomes among twin pregnancies conceived as a result of different types of fertility treatments with those of spontaneously conceived twin pregnancies. Retrospective Cohort. Population-based analysis. Population-based analysis of twin pregnancies in the United States based on their mode of conception using the natality data from the National Center for Health Statistics from the Centers for Disease Control and Prevention (from January 2015 through December 2017). None. Adverse neonatal and maternal outcomes. The overall prevalence of early adverse maternal outcomes and medical complications and obstetric complications including the risk of unplanned hysterectomy, intensive care unit admission, maternal blood transfusion, and perineal laceration were significantly higher in the fertility treatment group (including both ovulation induction/intrauterine insemination and assisted reproductive technology groups) compared with those of the spontaneous conception group, even after adjusting for several potential confounders. The risk of adverse composite neonatal outcomes was slightly lower in the spontaneous conception live twin birth group even after adjustment for several potential confounders. The rate of maternal and neonatal morbidity in twins conceived via different fertility treatments was slightly increased compared with those of twins conceived spontaneously. Because the absolute risks of maternal and neonatal morbidity were low, overall reassurance regarding these outcomes can be provided to the patients undergoing all types of fertility treatments. Resultados neonatales y maternos en embarazos gemelares estratificados por el modo de concepción en los Estados Unidos. Comparar los resultados neonatales y maternos en los embarazos gemelares concebidos como resultado de diferentes tipos de tratamientos de fertilidad con aquellos embarazos gemelares concebidos espontáneamente. Estudio retrospectivo de cohortes. Análisis poblacional. Análisis poblacional de embarazos gemelares en Estados Unidos basado en el modo de concepción utilizando datos de natalidad del centro nacional de estadísticas de salud a partir de los datos de los centros de prevención y control de enfermedades (Desde enero de 2015 hasta diciembre de 2017). Ninguna. resultados adversos neonatales y maternales. La prevalencia general de resultados adversos maternales tempranos y de complicaciones médicas y obstétricas, incluyendo el riesgo de histerectomía no p