Prognostic value of testosterone castration levels following androgen deprivation and high-dose radiotherapy in localized prostate cancer: Results from a phase III trial

Prognostic value of testosterone castration levels following androgen deprivation and high-dose radiotherapy in localized prostate cancer: Results from a phase III trial

•The optimal prognostic value of testosterone following ADT is controversial.•It remains unknown the impact of testosterone recovery after ADT and radiotherapy.•We studied testosterone kinetics in prostate cancer patients treated in a clinical trial.•Testosterone 

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Veröffentlicht in:Radiotherapy and oncology 2021-07, Vol.160, p.115-119
Hauptverfasser: Zapatero, Almudena, Álvarez, Ana, Guerrero, Araceli, Maldonado, Xavier, González San Segundo, Carmen, Cabeza, María A., Martín de Vidales, Carmen, Solé, Josep M., Pedro Olivé, Agustí, Casas, Francesc, Boladeras, Ana, Vázquez de la Torre, María L., Vara, Susana, Calvo, Felipe.A.
Format: Artikel
Sprache:eng
Schlagworte:
Androgen Antagonists - therapeutic use
Androgen deprivation therapy
Androgens
Castration
Humans
Male
Prognosis
Prostate cancer
Prostatic Neoplasms - drug therapy
Prostatic Neoplasms - radiotherapy
Radiotherapy
Testosterone
Testosterone level
Testosterone recovery
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Zusammenfassung:•The optimal prognostic value of testosterone following ADT is controversial.•It remains unknown the impact of testosterone recovery after ADT and radiotherapy.•We studied testosterone kinetics in prostate cancer patients treated in a clinical trial.•Testosterone 
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2021.04.018