An Antithymocyte Globulin-Free Conditioning Regimen Using Fludarabine and Cyclophosphamide Is Associated with Good Outcomes in Patients Undergoing Matched Related Family Donor Transplantation for Aplastic Anemia

An Antithymocyte Globulin-Free Conditioning Regimen Using Fludarabine and Cyclophosphamide Is Associated with Good Outcomes in Patients Undergoing Matched Related Family Donor Transplantation for Aplastic Anemia

•An antithymocyte globulin-free protocol using fludarabine and cyclophosphamide as conditioning for matched sibling donor transplantation in patients with aplastic anemia was evaluated.•Overall survival was reasonable at 75%, with >80% survival in patients age

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Veröffentlicht in:Transplantation and cellular therapy 2021-05, Vol.27 (5), p.409.e1-409.e6
Hauptverfasser: George, Biju, Lionel, Sharon, Selvarajan, Sushil, Abubacker, Fouzia N., Korula, Anu, Devasia, Anup J., Kulkarni, Uday, Lakshmi, Kavitha M., Sindhuvi, Eunice, Abraham, Aby, Mathews, Vikram
Format: Artikel
Sprache:eng
Schlagworte:
Aplastic anemia
Cyclophosphamide
Fludarabine
Survival
Transplantation
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Zusammenfassung:•An antithymocyte globulin-free protocol using fludarabine and cyclophosphamide as conditioning for matched sibling donor transplantation in patients with aplastic anemia was evaluated.•Overall survival was reasonable at 75%, with >80% survival in patients age
ISSN:2666-6367
2666-6367
DOI:10.1016/j.jtct.2021.01.029