On location for cannabinoid control of multimodal behavior

On location for cannabinoid control of multimodal behavior

In this issue of Neuron, Soria-Gomez et al. (2021) investigate whether activation of the type 1 cannabinoid receptor at specific subcellular locations within a single neural circuit produces multimodal behavior. Their results demonstrate that location matters: striatonigral mitochondrial CB1 drives...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 2021-05, Vol.109 (9), p.1416-1418
Hauptverfasser: McKeon, Paige N, Mathur, Brian N
Format: Artikel
Sprache:eng
Schlagworte:
Behavior
Cannabinoid CB1 receptors
Catalepsy
Kinases
Mitochondria
Pain
Pain perception
Plasma
Tetrahydrocannabinol
THC
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In this issue of Neuron, Soria-Gomez et al. (2021) investigate whether activation of the type 1 cannabinoid receptor at specific subcellular locations within a single neural circuit produces multimodal behavior. Their results demonstrate that location matters: striatonigral mitochondrial CB1 drives catalepsy while striatonigral plasma membrane CB1 receptors enable antinociception.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2021.04.013