Fructose determination in fruit juices using an electrosynthesized molecularly imprinted polymer on reduced graphene oxide modified electrode

•The concentration of fructose is indicative of the freshness of fruit juices.•Excessive fructose consumption is associated with several diseases.•The development of an electrochemical sensor for fructose detection is reported.•The proposed electrode showed good analytical performance for fructose detection.•The methodology developed was applied for fructose determination in fruit juices. The present work reports the development of a novel electrochemical sensor for the selective detection of fructose. The sensor was developed through electropolymerization of a molecularly imprinted polymer film on a reduced graphene oxide modified electrode. The modified electrode was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy, atomic force microscopy and RAMAN spectroscopy. Through the application of the modified electrode, the recognition of fructose molecules occurred in a concentration range of 1.0 × 10−14 to 1.0 × 10−11 mol L−1, under a Langmuir adsorption isothermal model. The sensitivity and limits of detection and quantification obtained for the sensor were 9.9 × 107 A L mol−1, 3.2 × 10−15 mol L−1 and 1.1 × 10−14 mol L−1, respectively. The analytical method used for the detection of fructose presented good reproducibility, stability and accuracy, and was successfully applied for the quantification of this sugar in orange, apple and grape juices.