An observational study of sleep in childhood post‐neonatal encephalopathy

Aim Neonatal encephalopathy (NE) is associated with altered cognitive, motor, sensory abilities and behavioural outcomes. This case‐control study aimed to assess whether Quality of Life (QoL) and sleep disorders are affected in older children following NE compared to age‐matched controls. Methods Children at school‐age post‐NE were recruited and compared to age‐matched controls. Sleep and QoL were assessed with the Pediatric Quality of Life Inventory and the Child Sleep Habit Questionnaire. Results One hundred children were recruited with an age range of 4–6 years, including children post‐NE (n=45) and age‐matched controls (n = 55). Significantly higher pathological sleep scores were evident in 58% of children post‐NE compared to controls (43.8 vs 40.2; p = 0.001). Children post‐NE had increased bedtime resistance (p = 0.028) and sleep anxiety (p = 0.01) compared to controls. Children in the post‐NE group had lower total QoL scores versus controls (mean score 82.5 vs 95.8; p