Survival Trends and Syndromic Esophageal Atresia

Survival Trends and Syndromic Esophageal Atresia

Presence of a syndrome (or association) is predictive of poor survival in esophageal atresia (EA). However, most reports rely on historical patient outcomes, limiting their usefulness when estimating risk for neonates born today. We hypothesized improved syndromic EA survival due to advances in neon...

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Veröffentlicht in:Pediatrics (Evanston) 2021-05, Vol.147 (5), p.1
Hauptverfasser: Tan Tanny, Sharman P, Beck, Cara, King, Sebastian K, Hawley, Alisa, Brooks, Jo-Anne, McLeod, Elizabeth, Hutson, John M, Teague, Warwick J
Format: Artikel
Sprache:eng
Schlagworte:
Atresia
Birth weight
Coronary artery disease
Diseases
Esophageal atresia
Esophagus
Heart diseases
Infants (Newborn)
Lethality
Neonatal diseases
Neonates
Pediatric research
Pediatrics
Regression analysis
Risk factors
Survival
Trends
Vertebrae
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Zusammenfassung:Presence of a syndrome (or association) is predictive of poor survival in esophageal atresia (EA). However, most reports rely on historical patient outcomes, limiting their usefulness when estimating risk for neonates born today. We hypothesized improved syndromic EA survival due to advances in neonatal care. A retrospective single-center review of survival in 626 consecutive patients with EA from 1980 to 2017 was performed. Data were collected for recognized risk factors: preterm delivery; birth weight
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2020-029884