Is presymptomatic ALS perivascular?
Increased activity in perivascular fibroblasts could precede motor-neuron degeneration and be a predictor of shorter survival in amyotrophic lateral sclerosis.
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Veröffentlicht in: | Nature medicine 2021-04, Vol.27 (4), p.585-586 |
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container_title | Nature medicine |
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creator | Kreple, Collin J. Schoch, Kathleen M. Miller, Timothy M. |
description | Increased activity in perivascular fibroblasts could precede motor-neuron degeneration and be a predictor of shorter survival in amyotrophic lateral sclerosis. |
doi_str_mv | 10.1038/s41591-021-01311-y |
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subjects | 631/378/1689/1285 692/617/375/364 Amyotrophic lateral sclerosis Biomarkers Biomedical and Life Sciences Biomedicine Blood vessels Cancer Research Cancer therapies Clinical trials Cytokines Degeneration Development and progression Fibroblasts Gene expression Health aspects Immunotherapy Infectious Diseases Kidney cancer Kinases Medical prognosis Metabolic Diseases Molecular Medicine Neurons Neurosciences News & Views news-and-views Pathogenesis Prognosis Proteins Transgenic animals |
title | Is presymptomatic ALS perivascular? |
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