Is presymptomatic ALS perivascular?

Is presymptomatic ALS perivascular?

Increased activity in perivascular fibroblasts could precede motor-neuron degeneration and be a predictor of shorter survival in amyotrophic lateral sclerosis.

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Bibliographische Detailangaben
Veröffentlicht in:Nature medicine 2021-04, Vol.27 (4), p.585-586
Hauptverfasser: Kreple, Collin J., Schoch, Kathleen M., Miller, Timothy M.
Format: Artikel
Sprache:eng
Schlagworte:
631/378/1689/1285
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Amyotrophic lateral sclerosis
Biomarkers
Biomedical and Life Sciences
Biomedicine
Blood vessels
Cancer Research
Cancer therapies
Clinical trials
Cytokines
Degeneration
Development and progression
Fibroblasts
Gene expression
Health aspects
Immunotherapy
Infectious Diseases
Kidney cancer
Kinases
Medical prognosis
Metabolic Diseases
Molecular Medicine
Neurons
Neurosciences
News & Views
news-and-views
Pathogenesis
Prognosis
Proteins
Transgenic animals
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Beschreibung
Zusammenfassung:Increased activity in perivascular fibroblasts could precede motor-neuron degeneration and be a predictor of shorter survival in amyotrophic lateral sclerosis.
ISSN:1078-8956
1546-170X
DOI:10.1038/s41591-021-01311-y