Serum sodium variation is a major determinant of peridialytic blood pressure trends in haemodialysis outpatients

Intradialytic hypotension (IDH) and peridialytic blood pressure (BP) trends are associated with morbidity and mortality in haemodialysis (HD) patients. We aimed to characterise the respective influence of volume status and small solutes variation on peridialytic systolic BP (SBP) trends during HD. W...

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Veröffentlicht in:	Scientific reports 2021-04, Vol.11 (1), p.7882-7882, Article 7882
Hauptverfasser:	Jaques, David A., Davenport, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4022/1585/104/1586 692/4022/1950/1544 Antihypertensives Blood pressure Body mass index Body water Body weight Calcium Dialysate Dialysis Hemodialysis Humanities and Social Sciences Hypotension Morbidity multidisciplinary Multidisciplinary Sciences Overweight Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Sodium Solutes Trends Ultrafiltration Urea Variation
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Zusammenfassung:	Intradialytic hypotension (IDH) and peridialytic blood pressure (BP) trends are associated with morbidity and mortality in haemodialysis (HD) patients. We aimed to characterise the respective influence of volume status and small solutes variation on peridialytic systolic BP (SBP) trends during HD. We retrospectively analysed the relative peridialytic SBP decrease in 647 prevalent outpatients attending for their mid-week session with corresponding pre- and post-HD bioelectrical impedance analysis. Mean SBP decreased by 10.5 ± 23.6 mmHg. Factors positively associated with the relative decrease in SBP were: serum sodium (Na) decrease, body mass index, serum albumin, dialysis vintage, ultrafiltration rate and urea Kt/V ( p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-86960-2