Can (or Should) We Treat Depression and Anxiety in Parkinson's Disease Algorithmically?

Martyna et al discuss whether depression and anxiety can be treted in Parkinson's disease algorithmically. Pontone and Mills have authored a well-written and extensively referenced Research that concludes that the answer is yes to each of these questions. Accordingly, they embark on an effort to operationalize care approaches for these common psychiatric symptoms. While some might disagree with their conclusions or the validity of their exercise, what is not up for debate is the profound importance of addressing depression and anxiety in Parkinson's disease-they often cause greater distress and disability than the classically described motor symptoms, and they can present significant clinical challenges that interplay with neurological management, thereby demanding a level of collaborative and interdisciplinary care that can be difficult to achieve.