PROGNOSTIC SIGNIFICANCE OF BLOOD MARKER OF HYPERTROPHY- CARDIOTROPHIN-1 WHEN CARRYING DIFFERENT VARIANTS OF ITS GENE IN MEN WITH ESSENTIAL HYPERTENSION

The aim: To improve diagnosis of essential hypertension with left ventricular hypertrophy and chronic heart failure in men citizens of Podillya region in Ukraine by determining the plasma levels of cardiotrophin-1 in patients with different CT-1 gene variants. Materials and methods: A total of 70 me...

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Veröffentlicht in:	Wiadomości lekarskie (1960) 2021, Vol.74 (2), p.273-277
Hauptverfasser:	Matokhniuk, Maryna O, Limanskiy, Oleksandr V, Maiko, Olena V, Zhebel, Vadym, Shevchuk, Oleksandra K, Palii, Irina K
Format:	Artikel
Sprache:	eng
Schlagworte:	Essential Hypertension Humans Hypertension Hypertrophy, Left Ventricular - genetics Male Prognosis Ukraine
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Zusammenfassung:	The aim: To improve diagnosis of essential hypertension with left ventricular hypertrophy and chronic heart failure in men citizens of Podillya region in Ukraine by determining the plasma levels of cardiotrophin-1 in patients with different CT-1 gene variants. Materials and methods: A total of 70 men with no signs of cardiovascular disease and 100 patients with essential hypertension were examined. Among those, 50 participants had hypertension and left ventricular hypertrophy. Other 50 patients had hypertension complicated by chronic heart failure. Results: It was established that in patients with essential hypertension the frequency of the pool of genotypes GA + AA is higher than the genotype GG (p
ISSN:	0043-5147
DOI:	10.36740/wlek202102118