Recent Changes in Durable Left Ventricular Assist Device Bridging to Heart Transplantation

This study evaluates the impact of the recent United Network for Organ Sharing (UNOS) allocation policy change on outcomes of patients bridged with durable left ventricular assist devices (LVADs) to orthotopic heart transplantation (OHT). Adults bridged to OHT with durable LVADs between 2010 and 201...

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Veröffentlicht in:ASAIO journal (1992) 2022-02, Vol.68 (2), p.197-204
Hauptverfasser: Srinivasan, Amudan J., Seese, Laura, Mathier, Michael A., Hickey, Gavin, Lui, Cecillia, Kilic, Arman
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Sprache:eng
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Zusammenfassung:This study evaluates the impact of the recent United Network for Organ Sharing (UNOS) allocation policy change on outcomes of patients bridged with durable left ventricular assist devices (LVADs) to orthotopic heart transplantation (OHT). Adults bridged to OHT with durable LVADs between 2010 and 2019 were included. Patients were stratified based on the temporal relationship of their OHT to the UNOS policy change on October 18, 2018. The primary outcome was early post-OHT survival. In total, 9,628 OHTs were bridged with durable LVADs, including 701 (7.3%) under the new policy. Of all OHTs performed during the study period, the proportion occurring following durable LVAD bridging decreased from 45% to 34% (p 
ISSN:1058-2916
1538-943X
DOI:10.1097/MAT.0000000000001436