The Accuracy of Incident Vertebral Fracture Detection in Children Using Targeted Case‐Finding Approaches

ABSTRACT Vertebral fractures are clinically important sequelae of a wide array of pediatric diseases. In this study, we examined the accuracy of case‐finding strategies for detecting incident vertebral fractures (IVF) over 2 years in glucocorticoid‐treated children (n = 343) with leukemia, rheumatic...

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Veröffentlicht in:	Journal of bone and mineral research 2021-07, Vol.36 (7), p.1255-1268
Hauptverfasser:	Ma, Jinhui, Siminoski, Kerry, Wang, Peiyao, Jaremko, Jacob L, Koujok, Khaldoun, Matzinger, Mary Ann, Shenouda, Nazih, Lentle, Brian, Alos, Nathalie, Cummings, Elizabeth A, Ho, Josephine, Houghton, Kristin, Miettunen, Paivi M, Scuccimarri, Rosie, Rauch, Frank, Ward, Leanne M
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy ANALYSIS/QUANTITATION OF BONE Back pain Bone mineral density Children Chiropractic medicine Complications DISEASES AND DISORDERS OF/RELATED TO BONE DXA FRACTURE RISK ASSESSMENT Fractures Glucocorticoids Nephrotic syndrome OSTEOPOROSIS Pain Patients PRACTICE/POLICY‐RELATED ISSUES Radiography Spine (lumbar) Vertebrae
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Zusammenfassung:	ABSTRACT Vertebral fractures are clinically important sequelae of a wide array of pediatric diseases. In this study, we examined the accuracy of case‐finding strategies for detecting incident vertebral fractures (IVF) over 2 years in glucocorticoid‐treated children (n = 343) with leukemia, rheumatic disorders, or nephrotic syndrome. Two clinical situations were addressed: the prevalent vertebral fracture (PVF) scenario (when baseline PVF status was known), which assessed the utility of PVF and low lumbar spine bone mineral density (LS BMD; Z‐score
ISSN:	0884-0431 1523-4681
DOI:	10.1002/jbmr.4294