Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg
A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. The indiscriminate uses of antibiotics, as well as their misuse, resulted in the selection of bacteria resistant to known antibiotic...
Gespeichert in:
| Veröffentlicht in: | Current microbiology 2021-05, Vol.78 (5), p.1926-1938 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1938 |
|---|---|
| container_issue | 5 |
| container_start_page | 1926 |
| container_title | Current microbiology |
| container_volume | 78 |
| creator | do Vale, Jean Parcelli Costa Vasconcelos, Mayron Alves Arruda, Francisco Vassiliepe Sousa Firmino, Nairley Cardoso Sá Pereira, Anna Luísa Andrade, Alexandre Lopes Saker-Sampaio, Silvana Sampaio, Alexandre Holanda Marinho, Emmanuel Silva Teixeira, Alexandre Magno Rodrigues Marinho, Márcia Machado Rodrigues, Tigressa Helena Soares Teixeira, Edson Holanda dos Santos, Hélcio Silva |
| description | A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. The indiscriminate uses of antibiotics, as well as their misuse, resulted in the selection of bacteria resistant to known antibiotics, for which it has little or no treatment. In this way, the strategies to combat the resistance of microorganisms are extremely important and, essential oils of
Croton
species have been extensively studied for this purpose. The aim of this study was to carry the evaluation of antibacterial, antibiofilm, antioxidant activities, and spectroscopic investigation of essential oil from
Croton piauhiensis
(EOCp). The EOCp exhibited antimicrobial activity against Gram-positive and Gram-negative bacteria with required MICs ranging from 0.15 to 5% (v/v). In addition, the MBC of the EOCp for
Staphylococcus aureus
ATCC 25923 and ATCC 700698, were 0.15 and 1.25%, respectively. Moreover, the EOCp significantly reduced significantly the biofilm production and the number of viable cells from the biofilm of all bacterial strains tested. The antioxidant potential of the EOCp showed EC
50
values ranging from 171.21 to 4623.83 μg/mL. The EOCp caused hemolysis (>45%) at the higher concentrations tested (1.25 to 5%), and minor hemolysis (17.6%) at a concentration of 0.07%. In addition, docking studies indicated
d
-limonene as a phytochemical with potential for antimicrobial activity. This study indicated that the EOCp may be a potential agent against infections caused by bacterial biofilms, and act as a protective agent against ROS and oxidative stress. |
| doi_str_mv | 10.1007/s00284-021-02449-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2507150378</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2507150378</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-8c25e416ab8819f46275fbd51170eb2df80e76aed53c281fecb79757b2fb8dbf3</originalsourceid><addsrcrecordid>eNp9kcFO3DAQhq2qqCy0L8ChitRLL4EZO147x9VqoUiL4NCeLTuxt0ZJvLUTBO_WW18Mwy5F4sDBssbzzT_W_xNygnCKAOIsAVBZlUAxn6qqS_xAZlgxWkJd40cyA1axUs45HpKjlG4BkNaAn8ghY0JSUcGM-NWd7iY9-jAUwRWLYfS9b2IwXneFHtrnl3DvWz2MxU0YbS5zJ6OrlPbFte8KF0NfLGMYs87W6-m3t0Pyqbj697frTotF3HwmB053yX7Z38fk1_nq5_JHub6-uFwu1mXDBB9L2VBuK5xrIyXWrppTwZ1pOaIAa2jrJFgx17blrKESnW2MqAUXhjojW-PYMfm-093G8GeyaVS9T43tOj3YMCVFOQjkkB3I6Lc36G2Y4pB_lymsuQCsIVN0R2VbUorWqW30vY4PCkE9BaF2QagchHoOQmEe-rqXnkxv2_8jL85ngO2AlFvDxsbX3e_IPgJ545RN</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2519570190</pqid></control><display><type>article</type><title>Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>do Vale, Jean Parcelli Costa ; Vasconcelos, Mayron Alves ; Arruda, Francisco Vassiliepe Sousa ; Firmino, Nairley Cardoso Sá ; Pereira, Anna Luísa ; Andrade, Alexandre Lopes ; Saker-Sampaio, Silvana ; Sampaio, Alexandre Holanda ; Marinho, Emmanuel Silva ; Teixeira, Alexandre Magno Rodrigues ; Marinho, Márcia Machado ; Rodrigues, Tigressa Helena Soares ; Teixeira, Edson Holanda ; dos Santos, Hélcio Silva</creator><creatorcontrib>do Vale, Jean Parcelli Costa ; Vasconcelos, Mayron Alves ; Arruda, Francisco Vassiliepe Sousa ; Firmino, Nairley Cardoso Sá ; Pereira, Anna Luísa ; Andrade, Alexandre Lopes ; Saker-Sampaio, Silvana ; Sampaio, Alexandre Holanda ; Marinho, Emmanuel Silva ; Teixeira, Alexandre Magno Rodrigues ; Marinho, Márcia Machado ; Rodrigues, Tigressa Helena Soares ; Teixeira, Edson Holanda ; dos Santos, Hélcio Silva</creatorcontrib><description>A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. The indiscriminate uses of antibiotics, as well as their misuse, resulted in the selection of bacteria resistant to known antibiotics, for which it has little or no treatment. In this way, the strategies to combat the resistance of microorganisms are extremely important and, essential oils of
Croton
species have been extensively studied for this purpose. The aim of this study was to carry the evaluation of antibacterial, antibiofilm, antioxidant activities, and spectroscopic investigation of essential oil from
Croton piauhiensis
(EOCp). The EOCp exhibited antimicrobial activity against Gram-positive and Gram-negative bacteria with required MICs ranging from 0.15 to 5% (v/v). In addition, the MBC of the EOCp for
Staphylococcus aureus
ATCC 25923 and ATCC 700698, were 0.15 and 1.25%, respectively. Moreover, the EOCp significantly reduced significantly the biofilm production and the number of viable cells from the biofilm of all bacterial strains tested. The antioxidant potential of the EOCp showed EC
50
values ranging from 171.21 to 4623.83 μg/mL. The EOCp caused hemolysis (>45%) at the higher concentrations tested (1.25 to 5%), and minor hemolysis (17.6%) at a concentration of 0.07%. In addition, docking studies indicated
d
-limonene as a phytochemical with potential for antimicrobial activity. This study indicated that the EOCp may be a potential agent against infections caused by bacterial biofilms, and act as a protective agent against ROS and oxidative stress.</description><identifier>ISSN: 0343-8651</identifier><identifier>EISSN: 1432-0991</identifier><identifier>DOI: 10.1007/s00284-021-02449-1</identifier><identifier>PMID: 33782740</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Anti-Bacterial Agents - pharmacology ; Anti-Infective Agents ; Antibiotics ; Antimicrobial activity ; Antimicrobial agents ; Antioxidants ; Antioxidants - pharmacology ; Bacteria ; Biofilms ; Biomedical and Life Sciences ; Biotechnology ; Croton ; Essential oils ; Gram-Negative Bacteria ; Gram-Positive Bacteria ; Hemolysis ; Life Sciences ; Limonene ; Microbial Sensitivity Tests ; Microbiology ; Microorganisms ; Oils & fats ; Oils, Volatile - pharmacology ; Oxidative stress</subject><ispartof>Current microbiology, 2021-05, Vol.78 (5), p.1926-1938</ispartof><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021</rights><rights>The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-8c25e416ab8819f46275fbd51170eb2df80e76aed53c281fecb79757b2fb8dbf3</citedby><cites>FETCH-LOGICAL-c375t-8c25e416ab8819f46275fbd51170eb2df80e76aed53c281fecb79757b2fb8dbf3</cites><orcidid>0000-0001-5527-164X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00284-021-02449-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00284-021-02449-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33782740$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>do Vale, Jean Parcelli Costa</creatorcontrib><creatorcontrib>Vasconcelos, Mayron Alves</creatorcontrib><creatorcontrib>Arruda, Francisco Vassiliepe Sousa</creatorcontrib><creatorcontrib>Firmino, Nairley Cardoso Sá</creatorcontrib><creatorcontrib>Pereira, Anna Luísa</creatorcontrib><creatorcontrib>Andrade, Alexandre Lopes</creatorcontrib><creatorcontrib>Saker-Sampaio, Silvana</creatorcontrib><creatorcontrib>Sampaio, Alexandre Holanda</creatorcontrib><creatorcontrib>Marinho, Emmanuel Silva</creatorcontrib><creatorcontrib>Teixeira, Alexandre Magno Rodrigues</creatorcontrib><creatorcontrib>Marinho, Márcia Machado</creatorcontrib><creatorcontrib>Rodrigues, Tigressa Helena Soares</creatorcontrib><creatorcontrib>Teixeira, Edson Holanda</creatorcontrib><creatorcontrib>dos Santos, Hélcio Silva</creatorcontrib><title>Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg</title><title>Current microbiology</title><addtitle>Curr Microbiol</addtitle><addtitle>Curr Microbiol</addtitle><description>A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. The indiscriminate uses of antibiotics, as well as their misuse, resulted in the selection of bacteria resistant to known antibiotics, for which it has little or no treatment. In this way, the strategies to combat the resistance of microorganisms are extremely important and, essential oils of
Croton
species have been extensively studied for this purpose. The aim of this study was to carry the evaluation of antibacterial, antibiofilm, antioxidant activities, and spectroscopic investigation of essential oil from
Croton piauhiensis
(EOCp). The EOCp exhibited antimicrobial activity against Gram-positive and Gram-negative bacteria with required MICs ranging from 0.15 to 5% (v/v). In addition, the MBC of the EOCp for
Staphylococcus aureus
ATCC 25923 and ATCC 700698, were 0.15 and 1.25%, respectively. Moreover, the EOCp significantly reduced significantly the biofilm production and the number of viable cells from the biofilm of all bacterial strains tested. The antioxidant potential of the EOCp showed EC
50
values ranging from 171.21 to 4623.83 μg/mL. The EOCp caused hemolysis (>45%) at the higher concentrations tested (1.25 to 5%), and minor hemolysis (17.6%) at a concentration of 0.07%. In addition, docking studies indicated
d
-limonene as a phytochemical with potential for antimicrobial activity. This study indicated that the EOCp may be a potential agent against infections caused by bacterial biofilms, and act as a protective agent against ROS and oxidative stress.</description><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anti-Infective Agents</subject><subject>Antibiotics</subject><subject>Antimicrobial activity</subject><subject>Antimicrobial agents</subject><subject>Antioxidants</subject><subject>Antioxidants - pharmacology</subject><subject>Bacteria</subject><subject>Biofilms</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Croton</subject><subject>Essential oils</subject><subject>Gram-Negative Bacteria</subject><subject>Gram-Positive Bacteria</subject><subject>Hemolysis</subject><subject>Life Sciences</subject><subject>Limonene</subject><subject>Microbial Sensitivity Tests</subject><subject>Microbiology</subject><subject>Microorganisms</subject><subject>Oils & fats</subject><subject>Oils, Volatile - pharmacology</subject><subject>Oxidative stress</subject><issn>0343-8651</issn><issn>1432-0991</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kcFO3DAQhq2qqCy0L8ChitRLL4EZO147x9VqoUiL4NCeLTuxt0ZJvLUTBO_WW18Mwy5F4sDBssbzzT_W_xNygnCKAOIsAVBZlUAxn6qqS_xAZlgxWkJd40cyA1axUs45HpKjlG4BkNaAn8ghY0JSUcGM-NWd7iY9-jAUwRWLYfS9b2IwXneFHtrnl3DvWz2MxU0YbS5zJ6OrlPbFte8KF0NfLGMYs87W6-m3t0Pyqbj697frTotF3HwmB053yX7Z38fk1_nq5_JHub6-uFwu1mXDBB9L2VBuK5xrIyXWrppTwZ1pOaIAa2jrJFgx17blrKESnW2MqAUXhjojW-PYMfm-093G8GeyaVS9T43tOj3YMCVFOQjkkB3I6Lc36G2Y4pB_lymsuQCsIVN0R2VbUorWqW30vY4PCkE9BaF2QagchHoOQmEe-rqXnkxv2_8jL85ngO2AlFvDxsbX3e_IPgJ545RN</recordid><startdate>20210501</startdate><enddate>20210501</enddate><creator>do Vale, Jean Parcelli Costa</creator><creator>Vasconcelos, Mayron Alves</creator><creator>Arruda, Francisco Vassiliepe Sousa</creator><creator>Firmino, Nairley Cardoso Sá</creator><creator>Pereira, Anna Luísa</creator><creator>Andrade, Alexandre Lopes</creator><creator>Saker-Sampaio, Silvana</creator><creator>Sampaio, Alexandre Holanda</creator><creator>Marinho, Emmanuel Silva</creator><creator>Teixeira, Alexandre Magno Rodrigues</creator><creator>Marinho, Márcia Machado</creator><creator>Rodrigues, Tigressa Helena Soares</creator><creator>Teixeira, Edson Holanda</creator><creator>dos Santos, Hélcio Silva</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5527-164X</orcidid></search><sort><creationdate>20210501</creationdate><title>Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg</title><author>do Vale, Jean Parcelli Costa ; Vasconcelos, Mayron Alves ; Arruda, Francisco Vassiliepe Sousa ; Firmino, Nairley Cardoso Sá ; Pereira, Anna Luísa ; Andrade, Alexandre Lopes ; Saker-Sampaio, Silvana ; Sampaio, Alexandre Holanda ; Marinho, Emmanuel Silva ; Teixeira, Alexandre Magno Rodrigues ; Marinho, Márcia Machado ; Rodrigues, Tigressa Helena Soares ; Teixeira, Edson Holanda ; dos Santos, Hélcio Silva</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-8c25e416ab8819f46275fbd51170eb2df80e76aed53c281fecb79757b2fb8dbf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Anti-Infective Agents</topic><topic>Antibiotics</topic><topic>Antimicrobial activity</topic><topic>Antimicrobial agents</topic><topic>Antioxidants</topic><topic>Antioxidants - pharmacology</topic><topic>Bacteria</topic><topic>Biofilms</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Croton</topic><topic>Essential oils</topic><topic>Gram-Negative Bacteria</topic><topic>Gram-Positive Bacteria</topic><topic>Hemolysis</topic><topic>Life Sciences</topic><topic>Limonene</topic><topic>Microbial Sensitivity Tests</topic><topic>Microbiology</topic><topic>Microorganisms</topic><topic>Oils & fats</topic><topic>Oils, Volatile - pharmacology</topic><topic>Oxidative stress</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>do Vale, Jean Parcelli Costa</creatorcontrib><creatorcontrib>Vasconcelos, Mayron Alves</creatorcontrib><creatorcontrib>Arruda, Francisco Vassiliepe Sousa</creatorcontrib><creatorcontrib>Firmino, Nairley Cardoso Sá</creatorcontrib><creatorcontrib>Pereira, Anna Luísa</creatorcontrib><creatorcontrib>Andrade, Alexandre Lopes</creatorcontrib><creatorcontrib>Saker-Sampaio, Silvana</creatorcontrib><creatorcontrib>Sampaio, Alexandre Holanda</creatorcontrib><creatorcontrib>Marinho, Emmanuel Silva</creatorcontrib><creatorcontrib>Teixeira, Alexandre Magno Rodrigues</creatorcontrib><creatorcontrib>Marinho, Márcia Machado</creatorcontrib><creatorcontrib>Rodrigues, Tigressa Helena Soares</creatorcontrib><creatorcontrib>Teixeira, Edson Holanda</creatorcontrib><creatorcontrib>dos Santos, Hélcio Silva</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Current microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>do Vale, Jean Parcelli Costa</au><au>Vasconcelos, Mayron Alves</au><au>Arruda, Francisco Vassiliepe Sousa</au><au>Firmino, Nairley Cardoso Sá</au><au>Pereira, Anna Luísa</au><au>Andrade, Alexandre Lopes</au><au>Saker-Sampaio, Silvana</au><au>Sampaio, Alexandre Holanda</au><au>Marinho, Emmanuel Silva</au><au>Teixeira, Alexandre Magno Rodrigues</au><au>Marinho, Márcia Machado</au><au>Rodrigues, Tigressa Helena Soares</au><au>Teixeira, Edson Holanda</au><au>dos Santos, Hélcio Silva</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg</atitle><jtitle>Current microbiology</jtitle><stitle>Curr Microbiol</stitle><addtitle>Curr Microbiol</addtitle><date>2021-05-01</date><risdate>2021</risdate><volume>78</volume><issue>5</issue><spage>1926</spage><epage>1938</epage><pages>1926-1938</pages><issn>0343-8651</issn><eissn>1432-0991</eissn><abstract>A large number of infections are caused by Gram-positive and Gram-negative multi-resistant bacteria worldwide, adding up to a figure of around 700,000 deaths per year. The indiscriminate uses of antibiotics, as well as their misuse, resulted in the selection of bacteria resistant to known antibiotics, for which it has little or no treatment. In this way, the strategies to combat the resistance of microorganisms are extremely important and, essential oils of
Croton
species have been extensively studied for this purpose. The aim of this study was to carry the evaluation of antibacterial, antibiofilm, antioxidant activities, and spectroscopic investigation of essential oil from
Croton piauhiensis
(EOCp). The EOCp exhibited antimicrobial activity against Gram-positive and Gram-negative bacteria with required MICs ranging from 0.15 to 5% (v/v). In addition, the MBC of the EOCp for
Staphylococcus aureus
ATCC 25923 and ATCC 700698, were 0.15 and 1.25%, respectively. Moreover, the EOCp significantly reduced significantly the biofilm production and the number of viable cells from the biofilm of all bacterial strains tested. The antioxidant potential of the EOCp showed EC
50
values ranging from 171.21 to 4623.83 μg/mL. The EOCp caused hemolysis (>45%) at the higher concentrations tested (1.25 to 5%), and minor hemolysis (17.6%) at a concentration of 0.07%. In addition, docking studies indicated
d
-limonene as a phytochemical with potential for antimicrobial activity. This study indicated that the EOCp may be a potential agent against infections caused by bacterial biofilms, and act as a protective agent against ROS and oxidative stress.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33782740</pmid><doi>10.1007/s00284-021-02449-1</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0001-5527-164X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0343-8651 |
| ispartof | Current microbiology, 2021-05, Vol.78 (5), p.1926-1938 |
| issn | 0343-8651 1432-0991 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2507150378 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Anti-Bacterial Agents - pharmacology Anti-Infective Agents Antibiotics Antimicrobial activity Antimicrobial agents Antioxidants Antioxidants - pharmacology Bacteria Biofilms Biomedical and Life Sciences Biotechnology Croton Essential oils Gram-Negative Bacteria Gram-Positive Bacteria Hemolysis Life Sciences Limonene Microbial Sensitivity Tests Microbiology Microorganisms Oils & fats Oils, Volatile - pharmacology Oxidative stress |
| title | Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T12%3A05%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20Antimicrobial%20and%20Antioxidant%20Potential%20of%20Essential%20Oil%20from%20Croton%20piauhiensis%20M%C3%BCll.%20Arg&rft.jtitle=Current%20microbiology&rft.au=do%20Vale,%20Jean%20Parcelli%20Costa&rft.date=2021-05-01&rft.volume=78&rft.issue=5&rft.spage=1926&rft.epage=1938&rft.pages=1926-1938&rft.issn=0343-8651&rft.eissn=1432-0991&rft_id=info:doi/10.1007/s00284-021-02449-1&rft_dat=%3Cproquest_cross%3E2507150378%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2519570190&rft_id=info:pmid/33782740&rfr_iscdi=true |