Predictors of outcome in super refractory status epilepticus

•Autoimmune encephalitis was the most common etiology of SRSE.•Early treatment of SRSE is imperative for good outcomes.•Continuous EEG monitoring and thorough etiological work-up is essential.•Protocol driven management in a younger age-group results in good outcomes in 1/3rd of cases. We conducted...

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Veröffentlicht in:Epilepsy & behavior 2021-05, Vol.118, p.107929-107929, Article 107929
Hauptverfasser: Jose, Jithu, Keni, Ravish R., Hassan, Haseeb, Menon, Ramshekhar, Sukumaran, Sajith, Cherian, Ajith, Radhakrishnan, Ashalatha
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Sprache:eng
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Zusammenfassung:•Autoimmune encephalitis was the most common etiology of SRSE.•Early treatment of SRSE is imperative for good outcomes.•Continuous EEG monitoring and thorough etiological work-up is essential.•Protocol driven management in a younger age-group results in good outcomes in 1/3rd of cases. We conducted this study to determine the clinical, electrophysiological and radiological predictors of outcome in Super Refractory Status Epilepticus (SRSE). Data of patients treated for SRSE between January 2000 and November 2019, archived prospectively in our SE registry were analyzed. Functional outcome was measured by Glasgow outcome score (GOS) at the time of hospital discharge and was divided into: good i.e. GOS ≥ 3 and bad outcome i.e. GOS 
ISSN:1525-5050
1525-5069
DOI:10.1016/j.yebeh.2021.107929