Zeolitic imidazolate framework-8/ fluorinated graphene coated SiO2 composites for pipette tip solid-phase extraction of chlorophenols in environmental and food samples

In this work, a novel composite adsorbent was successfully prepared by zeolite imidazolate framework-8/fluorinated graphene layer-by-layer covalently bonded on SiO2 microspheres, and followed to be packed into micro pipette tip for extraction of trace chlorophenols prior to their detection by high performance liquid chromatography (HPLC). The morphology and structure of adsorbent material was characterized by field emission scanning electron microscopy with energy dispersive spectrometer, X-ray diffraction, and N2 adsorption. The parameters including the amount of adsorbent, sampling volume, sampling rate, sample pH, and desorption solvent affected the extraction performance was systematically investigated by pipette tip solid-phase extraction (PT-SPE) coupled with HPLC analysis. Under the optimized condition, the linearity of this method ranged from 20 to 2000 ng mL−1 for chlorophenols (CPs) with determination coefficient higher than 0.99. The limit of detection (at a signal-to-noise ratio of 3) were in the range 2–20 ng mL−1 for tap water and black tea drinks, 0.2–2 μg g−1 for honey. The relative recoveries of the CPs from spiked samples ranged from 71.8% to 104.7%, with relative standard deviations less than 6.2%. The filled extraction tube exhibited good stability and reproducibility. The proposed method has been successfully used to detect CPs in water and drinks with satisfactory recoveries. [Display omitted] •ZIF-8/FG was layer-by-layer covalently bonded on SiO2 microspheres.•Incorporation of FG induced growth of ZIF-8 for enhanced extraction.•Excellent extraction performance was obtained towards chlorophenols by PT-SPE.