Vitamin D has no impact on outcomes after HSCT in children—A retrospective study

Vitamin D not only plays an important role in bone metabolism but is also involved in multiple immune‐mediated processes in the body which may be adversely affected in those with low levels. Most pediatric studies evaluating the association of vitamin D in patients undergoing allogeneic HSCT are sin...

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Veröffentlicht in:	Pediatric transplantation 2021-06, Vol.25 (4), p.e14008-n/a
Hauptverfasser:	Bajwa, Rajinder P. S., Taylor, Kimberly, Hoyt, Amanda, Kamboj, Manmohan K., Stanek, Joseph, Mahadeo, Kris M., Alsaedi, Hawazen, Abdel‐Azim, Hisham, O’Kane, Sara, Martin, Paul L., Stafford, Lauren A., Dvorak, Christopher C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Bone turnover Child Child, Preschool Children Female Graft rejection Graft vs Host Disease - epidemiology Graft vs Host Disease - etiology Graft-versus-host reaction Grafts GvHD Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - mortality HSCT Humans Infant Infant, Newborn Infections - epidemiology Infections - etiology Kaplan-Meier Estimate Length of Stay - statistics & numerical data Leukocytes (neutrophilic) Male Malignancy Outcome Assessment, Health Care Patients Pediatrics Recurrence Retrospective Studies Risk Factors Stem cell transplantation Vitamin D Vitamin D Deficiency - complications Vitamin D Deficiency - diagnosis Young Adult
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Zusammenfassung:	Vitamin D not only plays an important role in bone metabolism but is also involved in multiple immune‐mediated processes in the body which may be adversely affected in those with low levels. Most pediatric studies evaluating the association of vitamin D in patients undergoing allogeneic HSCT are single‐center studies. We present the results of retrospective study at 5 centers across the United States in pediatric patients undergoing allogeneic HSCT. (VDD) and (VDI) were defined by vitamin D levels of
ISSN:	1397-3142 1399-3046
DOI:	10.1111/petr.14008