Pre‐transfer/PCI with ticagrelor and heparin administration in STEMI patients may be beneficial but should we do more?

Key Points Ticagrelor and heparin administration to STEMI patients 80 min prior to PCI center arrival resulted in an improved incidence of TIMI 2–3 flow in the infarct related artery (IRA) compared with patients treated just prior to PCI. In the patients treated with pre‐PCI center ticagrelor and heparin, there was a lower incidence of definite stent thrombosis without an apparent bleeding penalty. Despite improved IRA T2–3 flow pre‐PCI in the pre‐hospital patients, there was no improvement in in‐hospital mortality (3.5 vs. 3.1%) or post‐PCI ST segment resolution.