Gut microbiota composition associated with hepatic fibrosis in non‐obese patients with non‐alcoholic fatty liver disease

Background and Aim Gut microbiota composition is associated with the pathogenesis of non‐alcoholic fatty liver disease. However, the association between gut microbiota composition and non‐alcoholic fatty liver disease in non‐obese patients remains unclear. We compared clinical parameters and gut mic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of gastroenterology and hepatology 2021-08, Vol.36 (8), p.2275-2284
Hauptverfasser: Iwaki, Michihiro, Kessoku, Takaomi, Ozaki, Anna, Kasai, Yuki, Kobayashi, Takashi, Nogami, Asako, Honda, Yasushi, Ogawa, Yuji, Imajo, Kento, Yoneda, Masato, Maeda, Ayako, Tanaka, Yoshiki, Nakajima, Shunji, Ohno, Hiroshi, Usuda, Haruki, Kawanaka, Miwa, Kawaguchi, Takumi, Torimura, Takuji, Kage, Masayoshi, Hyogo, Hideyuki, Takahashi, Hirokazu, Eguchi, Yuichiro, Aishima, Shinichi, Wada, Koichiro, Kobayashi, Noritoshi, Sumida, Yoshio, Saito, Satoru, Nakajima, Atsushi
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background and Aim Gut microbiota composition is associated with the pathogenesis of non‐alcoholic fatty liver disease. However, the association between gut microbiota composition and non‐alcoholic fatty liver disease in non‐obese patients remains unclear. We compared clinical parameters and gut microbiota profiles of healthy controls and non‐obese and obese patients with non‐alcoholic fatty liver disease. Methods We examined the clinical parameters and gut microbiota profiles by 16S rRNA sequences and short‐chain fatty acid levels in fecal samples from 51 non‐obese patients with non‐alcoholic fatty liver disease (body mass index
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.15487