Peri-intubation cardiac arrest in the Emergency Department: A National Emergency Airway Registry (NEAR) study

To determine the incidence of peri-intubation cardiac arrest through analysis of a multi-center Emergency Department (ED) airway registry and to report associated clinical characteristics. This is a secondary analysis of prospectively collected data (National Emergency Airway Registry) comprising ED endotracheal intubations (ETIs) of subjects >14 years old from 2016 to 2018. We excluded those with cardiac arrest prior to intubation. The primary outcome was peri-intubation cardiac arrest. Multivariable logistic regression generated adjusted odds ratios (aOR) of variables associated with this outcome, controlling for clinical features, difficult airway characteristics, and ETI modality. Of 15,776 subjects who met selection criteria, 157 (1.0%, 95% CI 0.9–1.2%) experienced peri-intubation cardiac arrest. Pre-intubation systolic blood pressure