Redox-coupled rhythm and brews

A genetically encoded real-time redox reporter reveals that H 2 O 2 -signaling peroxiredoxin (PRX) proteins couple yeast metabolic oscillations with the cell division cycle. This new PRX function suggests fresh avenues for exploring circadian regulation of cell division and cancer.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature chemical biology 2021-04, Vol.17 (4), p.373-374
1. Verfasser:	O’Neill, John S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/80/105 631/92/458 631/92/96 Biochemical Engineering Biochemistry Bioorganic Chemistry Cell Biology Cell Division Chemistry Chemistry and Materials Science Chemistry/Food Science Circadian rhythms Genetic code Hydrogen peroxide News & Views news-and-views Oscillations Oxidation-Reduction Peroxiredoxin Peroxiredoxins Ultradian Rhythm Yeasts
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Beschreibung
Zusammenfassung:	A genetically encoded real-time redox reporter reveals that H 2 O 2 -signaling peroxiredoxin (PRX) proteins couple yeast metabolic oscillations with the cell division cycle. This new PRX function suggests fresh avenues for exploring circadian regulation of cell division and cancer.
ISSN:	1552-4450 1552-4469
DOI:	10.1038/s41589-021-00777-8