The Association of Sleep Apnea and Cardiorespiratory Fitness With Long-Term Major Cardiovascular Events

The Association of Sleep Apnea and Cardiorespiratory Fitness With Long-Term Major Cardiovascular Events

To determine the risk of long-term major adverse cardiovascular events (MACE) when sleep-disordered breathing (SDB) and decreased cardiorespiratory fitness (CRF) co-occur. We included consecutive patients who underwent symptom-limited cardiopulmonary exercise tests between January 1, 2005, and Janua...

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Veröffentlicht in:Mayo Clinic proceedings 2021-03, Vol.96 (3), p.636-647
Hauptverfasser: Barillas-Lara, Maria Irene, Medina-Inojosa, Jose R., Kolla, Bhanu Prakash, Smith, Joshua R., Bonikowske, Amanda R., Allison, Thomas G., Olson, Thomas, Lopez-Jimenez, Francisco, Somers, Virend K., Caples, Sean M., Mansukhani, Meghna P.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Cardiorespiratory Fitness
Cardiovascular diseases
Complications and side effects
Coronary artery bypass
Coronary Artery Disease - diagnosis
Coronary Artery Disease - etiology
Coronary Artery Disease - physiopathology
Exercise Test - statistics & numerical data
Female
Health aspects
Heart attack
Humans
Male
Middle Aged
Polysomnography
Pulmonary ventilation
Risk Assessment
Risk Factors
Sleep apnea syndromes
Sleep Apnea, Obstructive - complications
Sleep Apnea, Obstructive - physiopathology
Stroke (Disease)
Transluminal angioplasty
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Beschreibung
Zusammenfassung:To determine the risk of long-term major adverse cardiovascular events (MACE) when sleep-disordered breathing (SDB) and decreased cardiorespiratory fitness (CRF) co-occur. We included consecutive patients who underwent symptom-limited cardiopulmonary exercise tests between January 1, 2005, and January 1, 2010, followed by first-time diagnostic polysomnography within 6 months. Patients were stratified based on the presence of moderate-to-severe SDB (apnea/hypopnea index ≥15 per hour) and decreased CRF defined as
ISSN:0025-6196
1942-5546
DOI:10.1016/j.mayocp.2020.03.040