Metabolic Regulation of Intestinal Stem Cell Homeostasis
The balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide...
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Veröffentlicht in: | Trends in cell biology 2021-05, Vol.31 (5), p.325-327 |
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creator | Wang, Dan Odle, Jack Liu, Yulan |
description | The balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases. |
doi_str_mv | 10.1016/j.tcb.2021.02.001 |
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Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases.</description><identifier>ISSN: 0962-8924</identifier><identifier>EISSN: 1879-3088</identifier><identifier>DOI: 10.1016/j.tcb.2021.02.001</identifier><identifier>PMID: 33648839</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Cell differentiation ; Cell fate ; Cell self-renewal ; Diet ; differentiation, nutrition ; Homeostasis ; intestinal stem cells ; Intestine ; Metabolic pathways ; Metabolism ; Nutritional status ; self-renewal ; Stem cells</subject><ispartof>Trends in cell biology, 2021-05, Vol.31 (5), p.325-327</ispartof><rights>2021 Elsevier Ltd</rights><rights>Copyright © 2021 Elsevier Ltd. 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Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases.</description><subject>Cell differentiation</subject><subject>Cell fate</subject><subject>Cell self-renewal</subject><subject>Diet</subject><subject>differentiation, nutrition</subject><subject>Homeostasis</subject><subject>intestinal stem cells</subject><subject>Intestine</subject><subject>Metabolic pathways</subject><subject>Metabolism</subject><subject>Nutritional status</subject><subject>self-renewal</subject><subject>Stem cells</subject><issn>0962-8924</issn><issn>1879-3088</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kEtr3DAUhUVpyEyT_IBugqGbbOxcPayR6KoMTSeQUshjLWTpOmiwrcSSC_33UZikiy66upvvHM79CPlMoaFA5eW-ya5rGDDaAGsA6Aeypmqjaw5KfSRr0JLVSjOxIp9S2gPAhlF-TFacS6EU12uifmK2XRyCq27xcRlsDnGqYl9dTxlTDpMdqruMY7XFYah2ccSYsk0hnZKj3g4Jz97uCXm4-n6_3dU3v35cb7_d1I4rmmsuGXQbsKhbj63iYL3koMErz2yvheCs23QoWy1dz1plLbTIlHed9EJTx0_IxaH3aY7PS5lkxpBcGWMnjEsyTOhWgCxsQb_8g-7jMpcPCtUySqkQtC0UPVBujinN2JunOYx2_mMomFetZm-KVvOq1QAzRWvJnL81L92I_m_i3WMBvh4ALCp-B5xNcgEnhz7M6LLxMfyn_gVvv4Xp</recordid><startdate>202105</startdate><enddate>202105</enddate><creator>Wang, Dan</creator><creator>Odle, Jack</creator><creator>Liu, Yulan</creator><general>Elsevier Ltd</general><general>Elsevier BV</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>202105</creationdate><title>Metabolic Regulation of Intestinal Stem Cell Homeostasis</title><author>Wang, Dan ; Odle, Jack ; Liu, Yulan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-3620b70ae95de5830ad63090d8d2af94432b7be6596cf258aa05e28dcb6d491c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Cell differentiation</topic><topic>Cell fate</topic><topic>Cell self-renewal</topic><topic>Diet</topic><topic>differentiation, nutrition</topic><topic>Homeostasis</topic><topic>intestinal stem cells</topic><topic>Intestine</topic><topic>Metabolic pathways</topic><topic>Metabolism</topic><topic>Nutritional status</topic><topic>self-renewal</topic><topic>Stem cells</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Dan</creatorcontrib><creatorcontrib>Odle, Jack</creatorcontrib><creatorcontrib>Liu, Yulan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Dan</au><au>Odle, Jack</au><au>Liu, Yulan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic Regulation of Intestinal Stem Cell Homeostasis</atitle><jtitle>Trends in cell biology</jtitle><addtitle>Trends Cell Biol</addtitle><date>2021-05</date><risdate>2021</risdate><volume>31</volume><issue>5</issue><spage>325</spage><epage>327</epage><pages>325-327</pages><issn>0962-8924</issn><eissn>1879-3088</eissn><abstract>The balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. 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subjects | Cell differentiation Cell fate Cell self-renewal Diet differentiation, nutrition Homeostasis intestinal stem cells Intestine Metabolic pathways Metabolism Nutritional status self-renewal Stem cells |
title | Metabolic Regulation of Intestinal Stem Cell Homeostasis |
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