Effects of Volatile Anesthetics on Postoperative Ischemic Stroke Incidence

Effects of Volatile Anesthetics on Postoperative Ischemic Stroke Incidence

Background Preclinical studies suggest that volatile anesthetics decrease infarct volume and improve the outcome of ischemic stroke. This study aims to determine their effect during noncardiac surgery on postoperative ischemic stroke incidence. Methods and Results This was a retrospective cohort stu...

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Veröffentlicht in:Journal of the American Heart Association 2021-03, Vol.10 (5), p.e018952-e018952, Article 018952
Hauptverfasser: Raub, Dana, Platzbecker, Katharina, Grabitz, Stephanie D., Xu, Xinling, Wongtangman, Karuna, Pham, Stephanie B., Murugappan, Kadhiresan R., Hanafy, Khalid A., Nozari, Ala, Houle, Timothy T., Kendale, Samir M., Eikermann, Matthias
Format: Artikel
Sprache:eng
Schlagworte:
anesthetics
Cardiac & Cardiovascular Systems
Cardiovascular System & Cardiology
cerebral ischemia
Life Sciences & Biomedicine
Original Research
retrospective studies
Science & Technology
stroke
stroke prevention
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Zusammenfassung:Background Preclinical studies suggest that volatile anesthetics decrease infarct volume and improve the outcome of ischemic stroke. This study aims to determine their effect during noncardiac surgery on postoperative ischemic stroke incidence. Methods and Results This was a retrospective cohort study of surgical patients undergoing general anesthesia at 2 tertiary care centers in Boston, MA, between October 2005 and September 2017. Exclusion criteria comprised brain death, age
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.120.018952