Testing deceased organ donors for infections: An organ procurement organization survey

Organ procurement organizations (OPO) test potential deceased organ donors for infectious diseases required by policy, but many also perform testing for additional infections. The current state of donor testing in the United States is unknown. We sent an IRB approved survey to all 57 U.S. OPOs using...

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Veröffentlicht in:American journal of transplantation 2021-05, Vol.21 (5), p.1924-1930
Hauptverfasser: Theodoropoulos, Nicole M., Greenwald, Melissa A., Chin‐Hong, Peter, Ison, Michael G.
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Sprache:eng
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Zusammenfassung:Organ procurement organizations (OPO) test potential deceased organ donors for infectious diseases required by policy, but many also perform testing for additional infections. The current state of donor testing in the United States is unknown. We sent an IRB approved survey to all 57 U.S. OPOs using REDCap. Descriptive statistics were performed. From the 57 OPOs, we received 46 (80.7%) unique responses with all 11 United Network of Organ Sharing regions represented. Forty of 46 (87%) OPO respondents consulted an Infectious Diseases physician when needed. Eighteen of 46 (39%) tested for West Nile virus (WNV) and 17 of 18 (94%) tested year‐round. Eleven of 46 (23.9%) tested for Strongyloides infection while 17 of 46 (37%) tested for Chagas disease. All OPOs performed prospective nucleic acid testing (NAT) for HIV, hepatitis B and hepatitis C on all donors. OPO testing of additional infections has increased since prior surveys but remains variable. Standardization of organ donor infectious diseases evaluation should be considered. Responses from organ procurement organizations to a survey on testing of all deceased organ donors for infectious diseases shows that less than 40% tested for West Nile virus and Chagas disease, 24% tested for Strongyloides infection, while 100% tested for HIV, hepatitis B, and hepatitis C.
ISSN:1600-6135
1600-6143
DOI:10.1111/ajt.16552