Uncovering the Mechanical Code of DNA Using ‘Loop-seq’

Uncovering the Mechanical Code of DNA Using ‘Loop-seq’

DNA mechanical properties play a critical role in different biological processes. Basu and coworkers described a method that measures DNA mechanics on the genome scale. Access to a high-throughput tool for measuring DNA mechanics opens up new possibilities to investigate this phenomenon with respect...

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Veröffentlicht in:Trends in genetics 2021-06, Vol.37 (6), p.494-495
1. Verfasser: Marzec, Marek
Format: Artikel
Sprache:eng
Schlagworte:
DNA looping
DNA mechanics
tightly bent DNA
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Zusammenfassung:DNA mechanical properties play a critical role in different biological processes. Basu and coworkers described a method that measures DNA mechanics on the genome scale. Access to a high-throughput tool for measuring DNA mechanics opens up new possibilities to investigate this phenomenon with respect to establishing the chromatin regulatory landscape.
ISSN:0168-9525
DOI:10.1016/j.tig.2021.02.004