Clinical and pathological diagnosis and comparison of benign and malignant eyelid tumors
To assess and compare demographic and clinical features of benign and malignant eyelid tumors from 2011 to 2018 in a tertiary medical center. The study was conducted retrospectively from medical records to compare demographic and clinical characteristics and recurrence of benign and malignant eyelid...
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Veröffentlicht in: | Journal francais d'ophtalmologie 2021-04, Vol.44 (4), p.537-543 |
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Sprache: | eng |
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Zusammenfassung: | To assess and compare demographic and clinical features of benign and malignant eyelid tumors from 2011 to 2018 in a tertiary medical center.
The study was conducted retrospectively from medical records to compare demographic and clinical characteristics and recurrence of benign and malignant eyelid tumors after obtaining institutional review board approval. A total of 428 eyelid tumors with histopathologic diagnoses were studied. Premalignant lesions were not included. The lesions were classified into two groups according to malignancy: benign and malignant eyelid lesions.
Among the 428 histopathologically confirmed eyelid lesions, 373 (87.1%) were benign and 55 (12.9%) were malignant. The patients with malignant eyelid tumors had a higher mean age at diagnosis than patients with benign eyelid tumors (P=0.012). The most common benign eyelid tumors were squamous papilloma (17.7%), xanthelasma (11.5%), and epidermal cysts (11.3%). The most common malignant eyelid tumors were basal cell carcinomas (65.5%), squamous cell carcinomas (14.5%), and sebaceous gland carcinomas (7.3%). There was no relative gender predominance between patients with benign and malignant eyelid tumors (P=0.287). Benign eyelid tumors were most commonly located on the right side and upper eyelid (P=0.027 and 0.036, respectively). Malignant tumors had a higher rate of recurrence (P=0.002).
Differentiation between benign and malignant eyelid lesions is important, since it may lead to cosmetic complications and serious morbidity, particularly in patients with malignant eyelid tumors.
Évaluer et comparer les caractéristiques démographiques et cliniques des tumeurs bénignes et malignes des paupières de 2011 à 2018 dans un centre médical tertiaire.
L’étude a été menée rétrospectivement à partir de l’emplacement des dossiers médicaux pour comparer les caractéristiques démographiques et cliniques et la récurrence des tumeurs bénignes et malignes des paupières. Au total, 428 tumeurs des paupières avec diagnostic histopathologique ont été étudiées. Les lésions précancéreuses n’étaient pas incluses. Les lésions ont été classées en deux groupes en fonction de la malignité: lésions bénignes et malignes des paupières.
Dans 428 lésions histopathologiques confirmées, 373 (87,1 %) étaient des lésions bénignes et 55 (12,9 %) étaient des lésions malignes. Les patients atteints de tumeurs malignes des paupières avaient un âge moyen au diagnostic plus élevé que les patients atteints de tumeurs bénignes des |
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ISSN: | 0181-5512 1773-0597 |
DOI: | 10.1016/j.jfo.2020.07.019 |