Liver choline metabolism and gene expression in choline-deficient mice offspring differ with gender
Choline is an important nutrient during pregnancy and lactation. Maternal choline deficiency in CD-1 mice lowers liver betaine levels in male offspring. By contrast, it increases elovl3 and vanin-1 mRNA levels in female offspring. Taken together, these observations suggest gender-specific responses...
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Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2021-02, Vol.85 (2), p.447-451 |
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creator | Miyachi, Yukino Akiyama, Kei Tsukuda, Yoshiko Kumrungsee, Thanutchaporn Yanaka, Noriyuki |
description | Choline is an important nutrient during pregnancy and lactation. Maternal choline deficiency in CD-1 mice lowers liver betaine levels in male offspring. By contrast, it increases elovl3 and vanin-1 mRNA levels in female offspring. Taken together, these observations suggest gender-specific responses to a choline-deficient diet. |
doi_str_mv | 10.1093/bbb/zbaa047 |
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source | Oxford University Press Journals All Titles (1996-Current) |
title | Liver choline metabolism and gene expression in choline-deficient mice offspring differ with gender |
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