Hepatic Scavenger Receptor Class B Type 1 Knockdown Reduces Atherosclerosis and Enhances the Antiatherosclerotic Effect of Brown Fat Activation in APOE3-Leiden.CETP Mice

[Figure: see text].

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Bibliographische Detailangaben
Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2021-04, Vol.41 (4), p.1474-1486
Hauptverfasser:	Zhou, Enchen, Li, Zhuang, Nakashima, Hiroyuki, Liu, Cong, Ying, Zhixiong, Foks, Amanda C., Berbée, Jimmy F.P., van Dijk, Ko Willems, Rensen, Patrick C.N., Wang, Yanan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - drug effects Adipose Tissue, Brown - metabolism Adrenergic beta-3 Receptor Agonists - pharmacology Animals Apolipoprotein E3 - genetics Apolipoprotein E3 - metabolism Atherosclerosis - genetics Atherosclerosis - metabolism Atherosclerosis - pathology Atherosclerosis - prevention & control Biomarkers - blood Cholesterol Ester Transfer Proteins - genetics Cholesterol Ester Transfer Proteins - metabolism Dioxoles - pharmacology Disease Models, Animal Gene Knockdown Techniques Humans Lipids - blood Lipolysis - drug effects Liver - metabolism Mice Mice, Inbred C57BL Mice, Transgenic Plaque, Atherosclerotic RNA Interference RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Scavenger Receptors, Class B - deficiency Scavenger Receptors, Class B - genetics
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