Palladium-Catalyzed Dual Coupling Reaction of 2‑Iodobiphenyls with o‑Bromoanilines through C–H Activation: An Approach for the Synthesis of Tribenzo[b,d,f]azepines

A novel and straightforward approach for the synthesis of tribenzo­[b,d,f]­azepines starting from 2-iodobiphenyls and 2-bromoanilines has been developed. A wide range of tribenzo­[b,d,f]­azepines were obtained in good to excellent yields via a cascade intermolecular palladium-catalyzed C–H activation/dual coupling reaction. C,C-palladacycles, which are generated by C–H activation of 2-iodobiphenyls, should be the reaction intermediates.