Analysis of plasma HER2 copy number in cell-free DNA of breast cancer patients: a comparison with HER2 extracellular domain protein level in serum

Background HER2 (human epidermal growth factor receptor 2) status has been evaluated in breast cancer (BC) tissues by immunohistochemistry or in situ hybridization. We evaluated HER2 copy number (CN) assay in plasma cell-free DNA (cfDNA) from blood samples and compared it with protein measurements o...

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Veröffentlicht in:	Breast cancer (Tokyo, Japan) Japan), 2021-05, Vol.28 (3), p.746-754
Hauptverfasser:	Qui, Shi, Takeshita, Takashi, Sueta, Aiko, Tomiguchi, Mai, Goto-Yamaguchi, Lisa, Hidaka, Kaori, Suzu, Ikuko, Yamamoto, Yutaka, Iwase, Hirotaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cancer Cancer Research Care and treatment Chemotherapy Comparative analysis DNA Epidermal growth factor Genetic aspects Genetic research Immunohistochemistry Medical research Medicine Medicine & Public Health Medicine, Experimental Metastasis Monoclonal antibodies Oncology Original Article Surgery Surgical Oncology
Online-Zugang:	Volltext
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