Control of nucleation and growth in protein crystal growth

The potential advantages of nucleation and growth control through temperature, rather than the addition of precipitants or removal of solvent, are discussed. A simple light scattering arrangement for the characterization of nucleation and growth conditions in solutions is described. The temperature...

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Veröffentlicht in:Journal of crystal growth 1988-07, Vol.90 (1-3), p.74-78
Hauptverfasser: Rosenberger, Franz, Meehan, Edward J.
Format: Artikel
Sprache:eng
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Zusammenfassung:The potential advantages of nucleation and growth control through temperature, rather than the addition of precipitants or removal of solvent, are discussed. A simple light scattering arrangement for the characterization of nucleation and growth conditions in solutions is described. The temperature dependence of the solubility of low ionic strength lysozyme solutions is applied in preliminary nucleation and growth experiments.
ISSN:0022-0248
1873-5002
DOI:10.1016/0022-0248(88)90300-4