Bringing distant DNA together

Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.

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Veröffentlicht in:Nature chemical biology 2021-02, Vol.17 (2), p.125-126
Hauptverfasser: Zhao, Haizhou, Kwok, Chun Kit
Format: Artikel
Sprache:eng
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Zusammenfassung:Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.
ISSN:1552-4450
1552-4469
DOI:10.1038/s41589-020-00705-2