Bringing distant DNA together
Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression.
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Veröffentlicht in: | Nature chemical biology 2021-02, Vol.17 (2), p.125-126 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets of YY1, and their interactions regulate DNA looping and gene expression. |
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ISSN: | 1552-4450 1552-4469 |
DOI: | 10.1038/s41589-020-00705-2 |