Relationship between plasma growth differentiation factor-15 level and estimated glomerular filtration rate in type 2 diabetes patients with and without albuminuria

To assess the relationship between growth differentiation factor-15 (GDF-15) levels and estimated glomerular filtration rate (eGFR) in type 2 diabetes mellitus (DM) patients with and without albuminuria. We examined 324 patients with type 2 DM in a cross-sectional study. eGFR was determined using eq...

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Veröffentlicht in:	Journal of diabetes and its complications 2021-04, Vol.35 (4), p.107849-107849, Article 107849
Hauptverfasser:	Chung, Jin Ook, Chung, Min Young, Park, Seon-Young, Cho, Dong Hyeok, Chung, Dong Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria - complications Albuminuria - diagnosis Body mass index Creatinine Cross-Sectional Studies Diabetes Diabetes mellitus, type 2 Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Glomerular Filtration Rate Growth Differentiation Factor 15 Hemoglobin Humans Hypertension Kidney diseases Plasma Regression analysis Renal Insufficiency, Chronic Variables
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Beschreibung
Zusammenfassung:	To assess the relationship between growth differentiation factor-15 (GDF-15) levels and estimated glomerular filtration rate (eGFR) in type 2 diabetes mellitus (DM) patients with and without albuminuria. We examined 324 patients with type 2 DM in a cross-sectional study. eGFR was determined using equations from creatinine (eGFRcr) and the combination of creatinine and cystatin C (eGFRcr-cys). The patients were classified into two groups based on urinary albumin: creatinine ratio (ACR): the normoalbuminuria group (urinary ACR
ISSN:	1056-8727 1873-460X
DOI:	10.1016/j.jdiacomp.2021.107849