Human group A rotavirus P[25] VP8 specifically binds to A-type histo-blood group antigen

Rotavirus (RV) is a common cause of acute gastroenteritis in young children. While P[8] and P[4] are the most prevalent RV genotypes in humans, other genotypes are also reported in human infections occasionally, including human P[25]. The glycan binding and structural characteristics of human P[25]...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2021-03, Vol.555, p.56-63
Hauptverfasser:	Li, Dandi, Wang, Mengxuan, Qi, Jianxun, Zhang, Qing, Wang, Hong, Pang, Lili, Sun, Xiaoman, Duan, Zhaojun
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Group Antigens - immunology Crystal structure Glycan binding specificity Histo-blood group antigen (HBGA) Human P rotavirus Humans Protein Binding Rotavirus - immunology Rotavirus Infections - virology VP8
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