The Mortality Risk of Proton Pump Inhibitors in 1.9 Million US Seniors: An Extended Cox Survival Analysis

Observational studies have linked proton pump inhibitors (PPIs) with increased risk of mortality and other safety outcomes, in contradiction with a recent PPI randomized controlled trial (RCT). Observational studies may be prone to reverse causality, where deaths are attributed to the treatment rath...

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Veröffentlicht in:	Clinical gastroenterology and hepatology 2022-04, Vol.20 (4), p.e671-e681
Hauptverfasser:	Baik, Seo H., Fung, Kin-Wah, McDonald, Clement J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged All-Cause Mortality Cohort Studies Extended Cox Regression Humans Propensity Score Proton Pump Inhibitors Proton Pump Inhibitors - adverse effects Protopathic Bias Survival Analysis Time-Varying Propensity Scores
Online-Zugang:	Volltext
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