Impact of seasonality, storage of semen, and sperm head‐shape on whole tissue methylation and expression of methylation responsive candidate genes in swine placenta and fetal livers from summer and winter breedings

Epigenetics includes the study of external factors that can influence the expression of genes by altering the accessibility of DNA through methylation. To investigate the epigenetic influence of season, sperm head shape, and semen storage on placental and fetal tissues, pregnancies were generated in...

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Veröffentlicht in:Molecular reproduction and development 2019-04, Vol.86 (4), p.465-475
Hauptverfasser: Rempel, Lea A., Krautkramer, Megan M., Parrish, John J., Miles, Jeremy R.
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Sprache:eng
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Zusammenfassung:Epigenetics includes the study of external factors that can influence the expression of genes by altering the accessibility of DNA through methylation. To investigate the epigenetic influence of season, sperm head shape, and semen storage on placental and fetal tissues, pregnancies were generated in the summer or winter using boar semen from either least or most sperm head shape change, collected during cool or warm seasons, and stored as cooled‐extended or cryopreserved. The lowest (p 
ISSN:1040-452X
1098-2795
DOI:10.1002/mrd.23125