Gluing Proteins for Targeted Degradation
Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6.
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| Veröffentlicht in: | Cancer cell 2021-01, Vol.39 (1), p.19-21 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Targeted protein degradation is an emerging technology for drug development. An article published in Nature reported a novel mechanism of targeted protein degradation triggered by small-molecule-induced polymerization of the oncogenic transcription factor BCL6. |
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| ISSN: | 1535-6108 1878-3686 |
| DOI: | 10.1016/j.ccell.2020.12.020 |