Copeptin reliably reflects longitudinal right ventricular function

Background Data is limited evaluating novel biomarkers in right ventricular dysfunction. Normal right heart function improves the prognosis of patients with heart failure. Therefore, this study investigates the association between the novel biomarker copeptin and right heart function compared to NT-...

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Veröffentlicht in:	Annals of clinical biochemistry 2021-07, Vol.58 (4), p.270-279
Hauptverfasser:	Harbrücker, Melissa, Natale, Michèle, Kim, Seung-Hyun, Müller, Julian, Ansari, Uzair, Huseynov, Aydin, Zworowsky, Max von, Borggrefe, Martin, Hoffmann, Ursula, Lang, Siegfried, Fatar, Marc, Roth, Thomas, Kittel, Maximilian, Bertsch, Thomas, Akin, Ibrahim, Behnes, Michael
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Zusammenfassung:	Background Data is limited evaluating novel biomarkers in right ventricular dysfunction. Normal right heart function improves the prognosis of patients with heart failure. Therefore, this study investigates the association between the novel biomarker copeptin and right heart function compared to NT-proBNP. Methods Patients undergoing routine echocardiography were enrolled prospectively. Right ventricular function was assessed by tricuspid annular plane systolic excursion (TAPSE) and further right ventricular and atrial parameters. Exclusion criteria were age under 18 years, left ventricular ejection fraction 24 mm: 5.20 pmol/L; grade II: TAPSE 18–24 mm: 8.10 pmol/L; grade III: TAPSE
ISSN:	0004-5632 1758-1001
DOI:	10.1177/0004563221989364