Association between diabetes and haematological malignancies: a population-based study

Aims/hypothesis Contemporary data for the association of diabetes with haematological malignancies are lacking. We evaluated the risk of developing haematological malignancies and subsequent mortality in individuals with diabetes compared with those without diabetes. Methods We conducted a populatio...

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Veröffentlicht in:Diabetologia 2021-03, Vol.64 (3), p.540-551
Hauptverfasser: Gong, Inna Y., Cheung, Matthew C., Read, Stephanie, Na, Yingbo, Lega, Iliana C., Lipscombe, Lorraine L.
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Sprache:eng
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Zusammenfassung:Aims/hypothesis Contemporary data for the association of diabetes with haematological malignancies are lacking. We evaluated the risk of developing haematological malignancies and subsequent mortality in individuals with diabetes compared with those without diabetes. Methods We conducted a population-based observational study using healthcare databases from Ontario, Canada. All Ontario residents 30 years of age or older free of cancer and diabetes between 1 January 1996 and 31 December 2015 were eligible for inclusion. Using Cox regression analyses, we explored the association between diabetes and the risk and mortality of haematological malignancies (leukaemia, lymphoma, multiple myeloma). The impact of timing on associations was evaluated with analyses stratified by time since diabetes diagnosis (
ISSN:0012-186X
1432-0428
DOI:10.1007/s00125-020-05338-7