Overexpression of CD168 is related to poor prognosis in oral squamous cell carcinoma

Objectives Receptor for hyaluronic acid (HA)‐mediated motility (RHAMM) is also known as CD168. This study proposed to elucidate the prognostic and clinicopathological significance of CD168 expression in oral squamous cell carcinoma (OSCC). Materials and methods Immune staining of a human tissue micr...

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Veröffentlicht in:Oral diseases 2022-03, Vol.28 (2), p.364-372
Hauptverfasser: Zhu, Su‐Wen, Wang, Shuo, Wu, Zhi‐Zhong, Yang, Qi‐Chao, Chen, De‐Run, Wan, Shu‐Cheng, Sun, Zhi‐Jun
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Sprache:eng
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Zusammenfassung:Objectives Receptor for hyaluronic acid (HA)‐mediated motility (RHAMM) is also known as CD168. This study proposed to elucidate the prognostic and clinicopathological significance of CD168 expression in oral squamous cell carcinoma (OSCC). Materials and methods Immune staining of a human tissue microarray and Western blot were used to reveal the expression level of CD168 in OSCC. Correlations between clinicopathological indexes and CD168 expression in OSCC patients were assessed. Results Increased expression of CD168 was detected in OSCC tissues. High expression of CD168 indicated worse survival of patients (p 
ISSN:1354-523X
1601-0825
DOI:10.1111/odi.13766