The “hypointense substantia nigra” sign. A novel MRI marker of progressive supranuclear palsy

•The “hypointense substantia nigra sign” (HSNS) is a novel MRI sign present in PSP.•The HSNS is a well-defined hypointense area at the medial substantia nigra in T1 images.•The HSNS is highly specific for progressive supranuclear palsy (PSP).•The HSNS is more specific but less sensitive for PSP comp...

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Veröffentlicht in:	Journal of the neurological sciences 2021-02, Vol.421, p.117286-117286, Article 117286
Hauptverfasser:	Constantinides, Vasilios C., Paraskevas, George P., Velonakis, Georgios, Toulas, Panagiotis, Karavasilis, Efstratios, Stefanis, Leonidas, Kapaki, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Hummingbird sign Hypointense substantia nigra sign Magnetic Resonance Imaging Movement disorders MRI Parkinsonism Progressive supranuclear palsy Substantia Nigra - diagnostic imaging Supranuclear Palsy, Progressive - diagnostic imaging
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Zusammenfassung:	•The “hypointense substantia nigra sign” (HSNS) is a novel MRI sign present in PSP.•The HSNS is a well-defined hypointense area at the medial substantia nigra in T1 images.•The HSNS is highly specific for progressive supranuclear palsy (PSP).•The HSNS is more specific but less sensitive for PSP compared to the “Hummingbird sign”.
ISSN:	0022-510X 1878-5883
DOI:	10.1016/j.jns.2020.117286