Making light work of lignan synthesis

Mimicking biosynthetic pathways can provide access to medicinally important natural products, but generating the reactive species used by nature can often be difficult. Now, a photoredox-based strategy has been developed to access a reactive radical intermediate postulated to be involved in complex...

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Veröffentlicht in:	Nature chemistry 2021-01, Vol.13 (1), p.7-9
Hauptverfasser:	Thach, Danny Q., Maimone, Thomas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	639/638/403/977 639/638/60 Analytical Chemistry Biochemical Phenomena Biochemistry Biosynthesis Chemistry Chemistry and Materials Science Chemistry/Food Science Cyclization Inorganic Chemistry Lignans Mimicry Natural products News & Views news-and-views Organic Chemistry Oxidation-Reduction Oxidative Stress Physical Chemistry
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Zusammenfassung:	Mimicking biosynthetic pathways can provide access to medicinally important natural products, but generating the reactive species used by nature can often be difficult. Now, a photoredox-based strategy has been developed to access a reactive radical intermediate postulated to be involved in complex lignan biosynthesis.
ISSN:	1755-4330 1755-4349
DOI:	10.1038/s41557-020-00604-y