No differences in hemostatic and endothelial activations between haploidentical and matched-donor hematopoietic stem cell transplantation in thalassemia disease

Hemostatic changes and endothelial activations have been recognized in beta-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, i...

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Veröffentlicht in:Thrombosis journal 2020-09, Vol.18 (1), p.21-21, Article 21
Hauptverfasser: Lertthammakiat, Surapong, Sitthirat, Peerasit, Anurathapan, Usanarat, Songdej, Duantida, Pakakasama, Samart, Chuansumrit, Ampaiwan, Putawornsub, Nattaphat, Sirasittikarn, Sawitt, Wantanawijarn, Sataporn, Kadegasem, Praguywan, Hongeng, Suradej, Sirachainan, Nongnuch
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Sprache:eng
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Zusammenfassung:Hemostatic changes and endothelial activations have been recognized in beta-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical HSCT. This report demonstrates that the levels of hemostatic and endothelial markers, including thrombin antithrombin complex, prothrombin fragment, D-dimer, von Willebrand factor antigen and thrombomodulin levels, were not significantly different between haploidentical and matched-donor HSCT patients.
ISSN:1477-9560
1477-9560
DOI:10.1186/s12959-020-00232-z