Emergence of a Highly Fit SARS-CoV-2 Variant

Early in the spread of SARS-CoV-2, the virus mutated, and the mutant form is now the most prevalent genotype worldwide. The vaccines currently being tested in clinical trials are based on the “ancestral” form of the virus. Will they be effective against the mutant form? Recent studies provide some c...

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Veröffentlicht in:	The New England journal of medicine 2020-12, Vol.383 (27), p.2684-2686
1. Verfasser:	Baric, Ralph S
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical trials Coronaviruses COVID-19 Disease transmission Genome, Viral Genotypes Humans Mutants Mutation Pandemics Pathogenesis Proteins SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Vaccines Virulence Viruses
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Early in the spread of SARS-CoV-2, the virus mutated, and the mutant form is now the most prevalent genotype worldwide. The vaccines currently being tested in clinical trials are based on the “ancestral” form of the virus. Will they be effective against the mutant form? Recent studies provide some clues.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMcibr2032888