The efficiency of hybrid perfusion SPECT/CT imaging in the diagnostic strategy of pulmonary thromboembolism

Ventilation/perfusion single photon emission computed tomography (V/Q SPECT) is recommended as a reference radionuclide method in pulmonary thromboembolism (PTE) diagnosis. However, there is some logistic, economic, and infectious concern about the study's ventilation part. This study aimed to...

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Veröffentlicht in:Hellenic journal of nuclear medicine 2020-09, Vol.23 (3), p.304
Hauptverfasser: Yildirim, Nilufer, Genc, Mustafa
Format: Artikel
Sprache:eng
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Zusammenfassung:Ventilation/perfusion single photon emission computed tomography (V/Q SPECT) is recommended as a reference radionuclide method in pulmonary thromboembolism (PTE) diagnosis. However, there is some logistic, economic, and infectious concern about the study's ventilation part. This study aimed to evaluate the effectiveness of hybrid perfusion SPECT with a low dose CT method in the diagnostic strategy of PTE. Two physicians reviewed 305 patients' data for this retrospective study. All patients had Q SPECT/CT data as initial imaging, and Ventilation SPECT was added to the selected patients' algorithm. The diagnostic performance and inter-observer agreement were determined for both Q SPECT and Q SPECT/CT methods. The final diagnosis was made by clinical decision with all tests and follow-up for at least 6-month. The majority (92%) of our study group were correctly diagnosed with the Q SPECT/CT method with excellent inter-observer agreements (κ=0.914). The sensitivity, specificity, and accuracy of methods were as follows; 92.2%, 76.3%, and 80.3% for Q SPECT; 96.1%, 94.5%, and 98.8% for Q SPECT/CT (P
ISSN:1790-5427
DOI:10.1967/s002449912209