The association between lipoprotein (a) and carotid atherosclerosis in patients with type 2 diabetes without pre-existing cardiovascular disease: A cross-sectional study

•Lipoprotein (a) has been considered a determinant of residual cardiovascular risk.•Higher Lp(a) was associated with carotid atherosclerosis in type 2 diabetic patients.•Higher Lp(a) level was associated with carotid atherosclerosis despite LDL-C50% of the surrounding IMT or its CIMT ≥1.5 mm. The pr...

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Veröffentlicht in:Diabetes research and clinical practice 2021-01, Vol.171, p.108622-108622, Article 108622
Hauptverfasser: Jun, Ji Eun, Kang, Hongsun, Hwang, You-Cheol, Ahn, Kyu Jeung, Chung, Ho-Yeon, Jeong, In-Kyung
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Sprache:eng
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Zusammenfassung:•Lipoprotein (a) has been considered a determinant of residual cardiovascular risk.•Higher Lp(a) was associated with carotid atherosclerosis in type 2 diabetic patients.•Higher Lp(a) level was associated with carotid atherosclerosis despite LDL-C50% of the surrounding IMT or its CIMT ≥1.5 mm. The presence of carotid atherosclerosis was defined as having CIMT ≥1.0 mm or carotid plaque. A total of 34.3% of patients had carotid atherosclerosis. The median Lp(a) level was significantly higher in subjects with carotid atherosclerosis (14.6 vs. 10.2 mg/dL, P 
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2020.108622